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Alternative Cancer Treatment, Gene and Breast Cancer

By: www.thealternativecancertreatment.com

Official figures have shown that between 5-10% of breast cancer is caused by the genetic makeup of an individual. Even though the percentage seems relatively low, the actual numbers are high enough to prompt many men and women to seek regular checkups. Yes, even men can contract breast cancer. This only occurs about .7% as often as women but it does happen and kills about 12,000 men each year.

Being female alone increases an individual's odds of contracting breast cancer relative to men by 133:1. A leading theory indicates that the most obvious and likely cause is the much greater estrogen and progesterone levels in females. These hormones aid in cell grown and seem to be involved when cell growth is uncontrollable, as in a disease such as breast cancer.

A genetic factor that might not seem to be genetic at first glance is the increase risk that comes with aging. As individuals grow older at what rate, and in what way is heavily influenced by one's genetics. Researchers in the field are determining that genetics determine the type of physiology that an individual has and that in turn plays a huge role in aging.

About 17% of invasive breast cancers occur in women in their 40s. But, a whopping 78% of those who contract the disease are in their 50s or older. That shouldn't be surprising by now. It's commonplace to observe that cancers are more likely the older one gets. Take care not to turn the statement around, though. It's not correct to say that 78% of women 50 or older get breast cancer. In fact, the number is about 1 in 12 or only 8%.

A major genetic risk factor doesn't come from normal genes; rather it comes from gene mutations. The most common of these gene mutations are labeled BRCA1 and BRCA1. These genes participate in making proteins that prevent cells from experiencing abnormal growth. Mutations or changes in these genes alter that ability thus opening the gate to increase the odds of contracting breast cancer. Some studies have determined that having the mutation places an individual at risk for developing breast cancer at up to 80%.

Typically those mutations are inherited and not produced by an individual's environment, diet or any other factors that could be controlled. Women whose mother's have had breast cancer are at a greater risk for developing the condition themselves. Obviously women do not inherit genes from siblings, but having a sibling that has contracted the disease does increase one's risk.

An additional gene mutation that could play a role is the ATM (ataxia-telangiectasia mutation). This involves a gene that plays a role in the repaid of DNA strands. The risk of breast cancer is doubled when another CHEK-2 gene mutates. Mutations in a gene called the p53 increase the odds because it works in the suppression of tumor growth. Fortunately, these occurrences all have an extremely low likelihood.

Until gene therapy advances there is nothing that a woman can do to alter the genetic endowment that they received. But being aware of the risk factors can aid in providing helpful information to doctors for diagnosis. Knowing that you have a family history containing an individual with Cowden Syndrome, for example, provides an incentive for one to seek checkups both early and often.

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