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Complete Information on Antiphospholipid syndrome with Treatment and Prevention

By: Alicia Stock

The syndrome of Antiphospholipid is a disorder of the coagulation, which causes clots of blood in arteries and veins, as well as of the complications connected by pregnancy like loss, serious delivery of preterm, or preeclampsia.Antiphospholipid syndrome is also called phospholipid antibody syndrome. Antiphospholipid syndrome can occur in patients without evidence of any definable associated disease or in association with systemic lupus erythematosus or another rheumatic or autoimmune disorder. Certain drugs can cause antiphospholipid antibodies to be produced in the blood, including antibiotics, cocaine, hydralazine, procainamide, and quinine. Nevertheless, the antiphospholipid antibody is not considered a normal blood protein and has been found in patients to be associated with a number of illnesses. In pregnancy, the placenta can be affected by small clots, and there is an increased risk of miscarriage, particularly in mid-pregnancy.

Antiphospholipid antibodies can be found also in the blood of individuals without some sickness process. The patients with the antiphospholipid can syndrome a mixture have of antibodies to molecules phospholipids called in their blood. Antiphosphilipid syndrome can cause many other problems. In antiphospholipid syndrome patients, the most common venous event is deep vein thrombosis of the lower extremities and the most common arterial event is stroke. Patients with antiphospholipid syndrome have developed abnormal symptoms while having antiphospholipid antibodies that are detectable with blood testing. When only the symptoms of the antiphospholipid syndrome occur, this is known as primary antiphospholipid syndrome. The secondary form occurs in association with another autoimmune disease, usually systemic lupus erythematosus. Both types are more common in women.

Certain people develop the red measles to have the lace with, winds style in theirs wrist and knee. Clots may also occur in the lung, sometimes following a clot in the leg, which breaks off and travels in the circulation until it lodges in part of the blood supply to the lung. Some clots occur in patients soon after starting on the oral contraceptive pill. Such arterial diseases occur commonly from atherosclerosis in old age, but in the antiphospholipid syndrome they can happen at a much younger age. Some patients may present with recurrent pregnancy losses often, but not always, in late second or third trimester of gestation. Both preeclampsia and intrauterine growth retardation have been observed concomitantly. Patients who present a history of previous pregnancy loss are subject to a new event more frequently. Some people experience a decrease in platelets, blood cells necessary for normal clotting.

Most often, Antiphospholipid syndrome is detected after a thrombotic event or recurrent miscarriages. Because many of the features of illness with anticardiolipin syndrome are associated with an abnormal grouping of normal blood clotting elements, treatment is often directed toward preventing clotting by thinning the blood. Patients with this disorder have an abnormal tendency to form blood clots. Often, this disease is treated by giving aspirin to inhibit platelet activation, and warfarin as an anticoagulant. Medications that thin the blood, such as heparin and warfarin, are used for treatment. Aspirin has an affect on platelets that inhibits their grouping and has also been used in low doses to thin the blood of selected patients. Other treatments include the use of intravenous gamma globulin for selected patients with histories of premature miscarriage and those with low blood-clotting elements during pregnancy.

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